Ctgf ligament

WebSep 17, 2024 · Cell–cell communication is an essential process to respond to biological stimuli and sustain the micro environmental homeostasis of human periodontal ligament stem cells (hPDLSCs). Connective tissue growth factor (CTGF), a critical secreted matrix protein, exhibits significant tasks in regulating the cell-cell and cell-matrix interactions. WebJun 3, 2011 · In addition, CCN2/CTGF is known to stimulate cellular differentiation and ECM synthesis as well in these cells [5], [6], [7]. However, the expression pattern and function of CCN2/CTGF in human ligament tissues remain unclear. Anterior cruciate ligament (ACL) injuries usually occur in the femoral attachment of ACL that contains interface cells [8].

The effect of adipose-derived stem cell sheets and CTGF on

WebThe impact of CTGF/CTGF+ASC treatment on tendon cell growth and differentiation. (a-d) Changes in relative abundance of genes involved in cell growth and differentiation in flexor tendons 14 days ... WebConnective tissue growth factor (CTGF) is covalently bound to latent TGFβ and is sequestered in the pericellular matrix (PCM) on heparan sulfate. ... At 10 weeks, surgical destabilisation of the joint, by cutting the … shubham singhal website https://charltonteam.com

Effects of connective tissue growth factor on human periodontal ...

WebObjectives: To clarify the role of cellular communication network factor 2/connective tissue growth factor (CCN2/CTGF) in periodontal tissue regeneration by investigating, the proliferative and tubulogenic responses of human endothelial cells obtained from the periodontal ligament to CCN2/CTGF. WebJun 3, 2011 · Abstract. Highlights: {yields} CCN2/CTGF localizes to the ligament-to-bone interface, but is not to the midsubstance region of human anterior cruciate ligament (ACL). {yields} Mechanical stretch induces higher increase of CCN2/CTGF gene expression and protein secretion in ACL interface cells compared with ACL midsubstance cells. {yields} … WebThese tissues, including teeth, periodontal ligament, alveolar bones, and dental pulp, present cell types and mechanical properties with great heterogeneity, which is challenging to reproduce in vitro. ... Phase (B) A scaffold area with 600 μm microchannels and PLGA microspheres loaded with CTGF was seeded with hPDLSCs for periodontal ligament ... shubham srivastava bothra classes

Frontiers Bioprinting and biomaterials for dental alveolar tissue ...

Category:Mechanical stretch increases CCN2/CTGF expression in

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Ctgf ligament

CTGF is a central mediator of tissue remodeling and

WebOct 5, 2005 · Important roles of CCN2/CTGF in the development and regeneration of periodontal tissue including theperiodontal ligament are suggested. BackgroundCCN2/CTGF is known to be involved in tooth germ development and periodontal tissue remodeling, as well as in mesenchymal tissue development and regeneration. In … WebNational Center for Biotechnology Information

Ctgf ligament

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WebJun 1, 2004 · Skin ligaments (SL) (L. retinacula cutis) are present extensively in the face, hands, feet, and in breast tissue, but have seldom been reported elsewhere in the body. The traditional histological ... WebDec 1, 2024 · Objectives. To clarify the role of cellular communication network factor 2/connective tissue growth factor (CCN2/CTGF) in periodontal tissue regeneration by investigating, the proliferative and tubulogenic responses of human endothelial cells obtained from the periodontal ligament to CCN2/CTGF.

WebSep 1, 2024 · Connective tissue growth factor (CTGF) is covalently bound to latent TGFβ and is sequestered in the pericellular matrix (PCM) on … WebJun 29, 2024 · Objective . This work is aimed at revealing the role and the molecular mechanism of connective tissue growth factor 2 (CTGF) in the osteoblast differentiation …

WebThe impact of CTGF/CTGF+ASC treatment on tendon cell growth and differentiation. (a-d) Changes in relative abundance of genes involved in cell growth and differentiation in … WebOct 5, 2005 · Connective tissue growth factor (CCN2/CTGF) is a cysteine-rich protein with a molecular weight of 36–38 kDa [1–3] and belongs to the CCN family, which stands for C …

WebDec 1, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN family and is a secreted matricellular and multifunctional protein. ... China) and …

WebDec 4, 2009 · Since fibrosis is observed in smokers’ gingiva, it was hypothesized that fibrosis was caused by nicotine in the periodontium. Therefore, in this study, we investigated the effects of nicotine on the induction of a profibrotic molecule, connective tissue growth factor (CCN2/CTGF), in human gingival fibroblasts (HGFs) and periodontal ligament … shubham sukhlecha.comWebThe influence of connective tissue growth factor on rabbit ligament injury repair ... Methods: A rabbit ACL injury model was used to study the effect of CTGF on ligament recovery. shubham sukhlecha classesWebJul 29, 2024 · The current study showed that CTGF could promote the recovery of an injured anterior cruciate ligament. It can upregulate mRNA and expression of TGF-β1, COL1, COL2, SOX9, and tissue inhibitor of TIMP-1, and downregulate mRNA and expression of MMP-13, suggesting that the curative effect of CTGF on injured rabbit ligaments is … the osteopathic consultancyWebJul 23, 2024 · The overall impact of ASCs and CTGF on early tendon healing response. The overall healing response was grossly compared among tendons from three repair groups … the osteopathic clinic barnetWebJul 23, 2024 · The overall impact of ASCs and CTGF on early tendon healing response. The overall healing response was grossly compared among tendons from three repair groups (N = 10 per group): Control (repaired ... shubham sukhlecha cs executiveWebJun 6, 2012 · CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, … shubham sukhlecha cs professionalthe osteopathic house