WebNational Center for Biotechnology Information WebEQS-News: MorphoSys AG / Key word(s): Miscellaneous MorphoSys Completes Enrollment of Phase 3 MANIFEST-2 Study of Pelabresib in Myelofibrosis with Topline Results Expected by End of 2024 04.04.2024 / 22:01 CET/CEST The issuer is solely responsible for the content of this announcement.. Media Release. Planegg/Munich, Germany, April 4, 2024. …
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Webtest_id gene_id gene locus sample_1 sample_2 status value_1 value_2 log2(fold_change) test_stat p_value q_value significant TSS1 XLOC_000001 Xkr4 chr1:3204754-3204833 q1 q2 OK 0 9459860 inf - 0.01975 0.09875 no TSS10 XLOC_000008 - chr1:3190858-3191434 q1 q2 OK 408511 420354 0.0412311 0.0469899 0.96715 0.96715 no TSS11 XLOC_000009 - … Pacritinib is a multikinase inhibitor of JAK2, FLT3, IRAK1, and CSF1R, with less myelosuppressive effect noted in the early-phase trials and further evidenced by the anemia response [25% achieved transfusion independence (TI)] and platelet improvement (35% increase in mean platelet count noted in those … See more Itacitinib is a selective JAK1 inhibitor being evaluated in MF under the premise that selective JAK1 inhibition will abrogate proinflammatory signaling without … See more The 5-year follow-up of the COMFORT-1 trial reported a median duration of approximately 3.2 years of spleen response, suggesting that the disease response to … See more Anemia independently predicts shortened survival in MF, and TD-anemia categorizes an MF patient in the higher-risk category regardless of the presence or absence … See more diashow ultimate 7
Paper: Pelabresib (CPI-0610) Combined with Ruxolitinib for JAK ...
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